Nicotine Tablets: Sublingual Nicotine Melts
Nicotine tablets and sublingual nicotine explained. How a 2mg BRST melt works, how fast it peaks, and how it differs from pouches and gum. 21+.
Key Takeaways
BRST is a 2mg sublingual melt, not a pouch and not chew-and-park gum.
Rose 2022: 14 min to peak vs 82.5 min for a 2mg lozenge.
Keep it still under the tongue about five minutes, back near the molars.
10 ingredients. Made in the USA. No smoke, no spit.
Not FDA NRT. 21+. Nicotine is addictive.
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Nicotine tablets are oral nicotine in a solid unit, not a bag and not a chew. BRST is a 2mg sublingual melt: it goes under the tongue, back near the molars, and you keep it still about five minutes. Published PK (Rose et al. 2022) put peak venous nicotine at 14 minutes and 4.4 ng/mL versus 82.5 minutes and 5.3 ng/mL for a 2mg Commit lozenge.
Other tablets exist (Nicorette Microtab, Rogue). They are not this formula. BRST is patented, 10 ingredients, made in a U.S. FDA-compliant facility, sold as an adult alternative, not as FDA NRT.
What does sublingual mean?
Sublingual is the floor of the mouth. The membrane is thin and the blood supply is close to the surface, so a drug can enter venous blood without going through the gut first. That is why sublingual delivery is used when speed matters. Buccal products (gum, lozenge, pouch) use thicker cheek or gum tissue and a longer dwell. More swallow, more first-pass, later Tmax. Background: the science of nicotine absorption.
Nicotine tablets vs pouches, gum, and lozenges
| Product | Dose | Tmax | Cmax | Source |
|---|---|---|---|---|
| Cigarette (venous) | 1 cigarette | 5–8 min | 15–30 ng/mL | Benowitz 2009 |
| BRST tablet | 2 mg | 14 min | 4.4 ng/mL | Rose 2022 (n=6) |
| Commit lozenge | 2 mg | 82.5 min | 5.3 ng/mL | Rose 2022 (same trial) |
| Nicorette gum (chew-and-park) | 4 mg | 50 min median | 4.4 ng/mL | Azzopardi 2022 |
| Nicorette mini-lozenge | 4 mg | 60 min median | 8.3 ng/mL | Azzopardi 2022 |
| Peppermint nicotine pouch | 4 mg | 60 min median | 8.5 ng/mL | Azzopardi 2022 |
| ZYN pouch | 3 mg | 61 min | 7.7 ng/mL | Lunell 2020 |
| ZYN pouch | 6 mg | 66 min | 14.7 ng/mL | Lunell 2020 |
| ZYN pouch | 8 mg | 59 min | 18.5 ng/mL | Lunell 2020 |
These are published figures from separate studies, not one trial of every product. Tmax is time to peak venous nicotine. Cmax is the peak concentration. A faster Tmax is the clock people feel. A higher Cmax is more nicotine in blood, not automatically a better product.
The tablet’s job is the early rise. A 6mg pouch can put more nicotine into blood by the one-hour mark. A cigarette still wins raw speed and Cmax. BRST is the fastest oral option we sell that is not a vape: 2mg, no smoke, no spit, no pouch.
How to use BRST nicotine tablets
Take one 2mg peppermint melt (20 per pack).
Place it under the tongue, back toward the molars.
Keep it still about five minutes. Do not chew. Do not park it in the cheek like gum.
Adults who want a second tablet take it after the first has finished.
Skip food and drink while it sits.
Rose’s subjective arm (n=24) saw craving drop from 2.6 to 1.0 at five minutes and a 4.2 / 7 relief score versus 4.6 for a usual cigarette. That is why the how-to is “keep still,” not “wait an hour.”
Tablet vs gum, lozenge, pouch, and Zyn
Vs gum: chew-and-park, ~33% extracted in Azzopardi 2022, median Tmax 50 min on 4mg.
Vs lozenge: the Rose 2022 head-to-head. 14 vs 82.5 min at 2mg.
Vs pouch: Lunell and Azzopardi put pouch Tmax at ~60 min.
Vs Zyn: 3/6/8mg ZYN Cmax 7.7 / 14.7 / 18.5 ng/mL at ~1 hour.
What is in a BRST tablet?
Ten pharmaceutical ingredients. Nine of them show up in food. Nicotine is the tenth. No tobacco leaf. Made in the USA in an FDA-compliant facility. The formula puts nicotine with oleic acid on silica so saliva can move it into sublingual tissue as the tablet comes apart. That mechanism is in the Rose paper and on the pharmacokinetics page.
Shop BRST nicotine melts.
Frequently asked questions
Are nicotine tablets the same as nicotine lozenges?
No. Lozenges are slow buccal dissolves. BRST is a sublingual melt. Rose 2022 measured both at 2mg.
Are nicotine tablets FDA-approved NRT?
Some tablets (Nicorette Microtab, in markets where sold as NRT) are medicines. BRST is not FDA NRT. It is a PMTA tobacco product for adults 21+.
How much nicotine is in a BRST tablet?
2mg per melt. The claim is delivery, not a 6mg label. Users from 6mg pouches often say the feel lands close.
How fast do nicotine tablets work?
BRST peaked at 14 minutes in Rose 2022, with measurable rise in the first four minutes (0.4 ng/mL/min). That is the number we have, not a class-wide tablet average.
Can I take more than one?
Adults can take tablets consecutively after the first has finished. Do not treat Cmax chasing like a game.
A note on what this is (and is not)
BRST is a PMTA tobacco product for adults 21+. It is not FDA-approved nicotine replacement therapy, and this page is not medical advice. Nicotine is addictive. Cross-study PK numbers come from different trials, doses, and use protocols. The only published head-to-head blood study of BRST is Rose et al. 2022 versus a 2mg Commit lozenge.
